多肽噬菌体展示

Peptide Phage Display.

噬菌体展示技术已被广泛地应用于生物学研究的各个方面 .利用它可融合表达多肽、蛋白质结构域和蛋白质 .尤其是多肽噬菌体展示 ,已被作为一种便利的研究工具去发现和研究那些与受体、酶、凝集素、抗体、核酸以及其他生物分子亲和的多肽配基和酶的底物专一性 ,该技术在药物的发现 。

Recently, phage display techniques have been applied to various biological aspects. Phage can be exploited to display peptides, protein domains and proteins on its surface. Especially peptide phage display is now well established as a tool for the search for peptides binding to antibodies, enzymes, receptors, lectins, nucleic acids or other target molecules and in studying the substrate specificity of enzymes. It has great potential for application in the areas of drug discovery, vaccine development and other pharmaceutical development.