新生儿高未结合胆红素血症心肌标志物及肝功能检测结果分析

Analysis of cardio makers and liver function in neonates with hyper unconjugated bilirubinemia

目的了解新生儿高未结合胆红素血症是否存在心肌和肝功能的损伤及损伤程度如何。方法分别用化学发光法检测心肌标志物CTn—I、MY0；用全自动生化分析仪检测CK、CK—MB、ALT、AST、ALP、r—GT、ALB、TBil、DBil。比较新生儿高未结合胆红素血症与对照组上述指标的差异。结果cTn—I、MYO、ALT、ALB两组间无显著性差异（P〉0．05）。CK、CK-MB、AST、r—GT、ALP等指标两组间有统计学差异（P〈0．05）。结论新生儿高未结合胆红素血症的心肌及肝功能有一定程度异常，但心肌和肝脏实质性损伤不显著。

Objectives To discuss if there have damage and degree of damage in heart function and liver function in neonates with hyper unconjugated bilirubinemia. Methods Detect the levels of cTn I, Myo by chemiluminescence, and CK, CK-MB, ALT, AST,ALP, r - GT, ALB, TBil, DBil by biochemistry in 40 neonates with hyper unconjugated bilirubinemia, use those without bilirubinemia as control group. Results There are no significant different in the levels of cTn-I, Myo, ALT and ALB between two groups（P 〉0.05）, but there are significant different in the levels of CK, CK-MB, AST, r - GT , ALP between two groups（P〈0. 05）.Conelusion There has somewhat abnormal in liver function and heaert function in neonates with hyper unconjugated bilirubinemia, however, there has no significant damage in liver and heaert.