青少年特发性脊柱侧凸女性患者的体重指数特征

Body mass index in girls with adolescent idiopathic scoliosis

目的探讨青少年特发性脊柱侧凸（AIS）女性患者与同年龄段健康女性在体重及体重指数（BMI）方面的差异。方法选择2005年1月至2007年1月就诊的613例AIS女性患者（病例组）以及449例同年龄段健康女性（对照组）进行研究，所有研究对象年龄12～16岁。观察指标包括身高、体重以及出生年月，根据上述指标计算出校正身高、BMI以及校正BMI。病例组的校正身高根据最大Cobb角采用Bjure公式进行校正。采用独立样本t检验对病例组及对照组的身高、体重、BMI以及校正BMI进行比较。结果病例组平均最大Cobb角为（31±11）（11～77）°。在每个年龄段，病例组的校正身高均高于对照组（P〈0．05），体重低于对照组（P〈0．01）。病例组12、13、14、15及16岁患者的BMI分别为（17．6±1．9）、（17．9±2．5）、（17．9±2．1）、（18．6±2．3）和（19．0±1．9）kg／m^2；而对照组对应年龄女性的BMI分别为（19．5±3．4）、（19．8±3．0）、（20．4±2．9）、（20．4±2．8）和（20．2±2．2）kg／m^2，均高于病例组（P〈0．01）。结论进入青春期后，AIS女性患者比同年龄段正常女性偏高偏瘦；BMI比同年龄段正常女性偏低，提示AIS女性患者在青春期存在异常生长模式。

Objective To investigate body weight and the body mass index （BMI） in girls with adolescent idiopathic scoliosis （AIS）. Methods Six hundred and thirteen AIS female patients admitted from January 2005 to January 2007 and 449 healthy girls were recruited for this study with a range of age from 12 to 16 years old. The direct indexes included body height, body weight and date of birth. The indirect indexes included corrected body height, BMI and corrected BMI. The corrected body heights of AIS patients were adjusted by using the greatest Cobb angle to correct for spinal deformity according to Bjure＇s formula. Two-tailed Student＇s test was used for group comparison. Results In the AIS patients, the maximum Cobb angle was （ 31 ±11 ） ± （ 11 ± to 77 ± ）. The corrected body height were significantly higher in AIS patients than in the normal controls from 12 to 16 years old （P 〈 0.05 ）. The body weight were significantly lower in AIS girls than in normal controls from 12 to 16 years of age （P 〈 0. 01 ）. From 12 to 16 years of age, theBMIwere （17.6±1.9）, （17.9 ±2.5）, （17.9 ±2. 1）, （18.6 ±2.3） and （19.0± 1.9） kg/m2 in AIS patients;while the BMI were （19.5 ±3.4）, （19.8 ±3.0）, （20.4 ±2.9）, （20.4 ± 2. 8） and （20. 2 ± 2. 2） kg/m^2 in normal controls. The BMI were significantly lower in AIS girls than the normal controls from 12 to 16 years of age （ P 〈 0. 001 ）. Conclusions After the onset of puberty, significantly longer corrected height, lower body weight and lower BMI were found in AIS patients. Results of this large-scale study revealed the presence of abnormal growth in AIS patients during peripubertal development.