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腹主动脉瘤破裂风险预测研究进展 被引量：1

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摘要 腹主动脉瘤（abdominal aortic aneurysm，AAA）是主动脉重大疾病，有自然破裂的危险，90％以上的破裂者可发生猝死。几十年来临床上一直将动脉瘤直径〉5．5cm，年增大〉1．0cm作为手术指征。根据Laplace定律，动脉瘤直径越大瘤壁所受的张力负荷越大，破裂风险也越高。但近年国外临床研究显示，有约25％直径〈5．5cm的动脉瘤也会发生破裂，小AAA的破裂率为1．0％-2．2％／年，而直径〉5．5cm的AAA中约有50％并不发生破裂。所以根据直径预测AAA的破裂风险并不精确，更科学更准确地阐明AAA破裂因素已成为大动脉疾病研究的一个重要方向。本文就几方面作一综述。
作者 辛群 陆清声 景在平
机构地区 第二军医大学附属长海医院血管外科
出处 《中华外科杂志》 CAS CSCD 北大核心 2008年第8期630-631,共2页 Chinese Journal of Surgery
关键词 腹主动脉瘤破裂 风险预测 Laplace定律 动脉瘤直径 AORTIC 临床研究 大动脉疾病 重大疾病
分类号 R686 [医药卫生—骨科学]
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参考文献15

  • 1Lederle FA, Wilson SE, Johnson GR, et al. Immediate repair compared with surveillance of small abdominal aortic aneurysms. N Engl J Med,2002, 346 : 1437-1444.
  • 2Venkatasubramaniam AK, Fagan M J, Mehta T, et al. A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms. Eur J Vasc Endovasc Surg,2004,28 : 168-176.
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同被引文献7

  • 1吴在德 吴肇汉.外科学[M].北京:人民卫生出版社,2004.570.
  • 2Wassef M, Baxter BT, Chishohn RL, et al. Pathogenesis of abdominal aortic aneurysm: a multidisciplinary research prcgtam supported by the National Heart, Lung, and Blood Institute [J]. J Vasc Surg,2001,34: 730-738.
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  • 4Akkersdijk GJ,Bockel JH.Ruptured abdominal aortlcaneurysm , initi',d misdlagnosis and the effect on treatment [J]. EurJ Surg, 1998,64:29.
  • 5Masaki Ando, Tsuguo Igari, Hitoshi Yokoyama, et al. CT Features of Chronic Contained Rupture of an Abdominal Aortic Aneurysm[J ]. Ann Thorac Cardiovasc Surg J 2003,9(4):274-278.
  • 6刘仁贵,赵纪春.腹主动脉瘤的发病机理及治疗进展[J].中国普外基础与临床杂志,2008,15(6):422-425. 被引量：9
  • 7景在平,冯睿,冯翔.腹主动脉瘤破裂的误诊误治[J].临床误诊误治,2001,14(1):1-4. 被引量：9

引证文献1

中华外科杂志
2008年 第8期

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