ACE基因多态性与急性缺血性中风始发证候相关性的研究

Exploration on the Relevance of the ACE Gene Polymorphism and Acute Ischemic Stroke Predicate Syndrome

目的:探讨ACE基因多态性与急性缺血性中风始发证候的相关性。方法:选择发病7天之内急性缺血性中风患者118例,进行ACE基因(D/I)多态性检测,同时进行证候分型,分析两者之间的相关性。结果:单因素分析结果显示,非II型痰证比例明显升高,χ2=4.882,P=0.036;非DD型气虚证比例明显升高,χ2=4.750,P=0.036;组间比较有统计学意义。结论:D等位基因与痰证、I等位基因与气虚证的发生可能存在相关性。

Objective： Explore the ACE gene polymorphism and acute ischemic stroke predicate syndrome relevance. Methods： The incidence within seven days of acute ischemic stroke patients with 118 cases, the ACE gene （I / D） polymorphism detection, simultaneously syndrome typing, analysis between the two relevant. Results ： Univariate analysis showed that non - certified Type Ⅱ sputum ratio increased significantly, X^2 = 4. 882, P = 0. 036; Non - DD- deficiency syndromes ratio increased significantly, X^2 = 4. 750, P = 0.036; Differences between the groups was statistically significance. Conclusion ： D allele and sputum card, I allele and the incidence of deficiency syndromes possible relevance.