肿瘤坏死因子拮抗剂治疗类风湿关节炎
摘要
类风湿关节炎(rheumatoid arthritis,RA)是以滑膜炎为主要表现的自身免疫病,可导致进行性关节的侵蚀破坏和功能丧失。几十年来,对于该病的诊疗观念已经有了显著变化,从”控制症状”发展为”改变病情”,并强调早期诊断和早期治疗的重要性。2002年,美国风湿病学院(American College of rheumatology,ACR)发表的RA治疗指南。
出处
《美国医学会杂志(中文版)》
2008年第2期125-128,共4页
The Journal of the American Medical Association(Chinese Edition)
参考文献23
-
1American College of Rheumatology Subcommittee on Rheumatoid Arthritis Guidelines. Guidelines for the management of rheumatoid arhritis: 2002 Update. Arthritis Rheum. 2002 ;46 : 328-346.
-
2Shealy DJ, Visvanathan S. Anti-TNF antibodies: lessons from the past, roadmap for the future. Handb Exp Pharmacol. 2008 ;181:101-29.
-
3Maini RN, Breedveld FC, Kalden JR, et al. Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor α monoclonal antibody combined with lowdose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum. 1998 ;41:1552-1563.
-
4Maini R, St Clair EW, Breedveld F, et al. Infliximab ( chimeric antitumour necrosis factor alpha monoclonal antibody ) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate : a randomised phase III trial. ATTRACT Study Group. Lancet. 1999 ;354:1932- 1939.
-
5Combination of infliximab and methotrexate therapy for early rheumatoid arthritis : a randomized, controlled triM. Arthritis Rheum 2004 ; 50 : 3432- 3443.
-
6Bathon JM, Martin RW, Fleischmann RM, et al. A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. N Engl J Med. 2000 ;343 : 1586-1593.
-
7Breedveld FC, Weisman MH, Kavanaugh AF, et al. The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. Arthritis Rheum. 2006 ; 54:26- 37.
-
8Furst DE, Breedveld FC, Kalden JR, et al. Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2007. Ann Rheum Dis. 2007 ;66 ( Suppl 3 ) : iii2-22.
-
9Chang J, Girgis L. Clinical use of anti-TNF-alpha biological agents--a guide for GPs. Aust Fam Physician. 2007 ;36:1035-1038.
-
10Kei Ikeda, Sally Cox, Paul Emery. Biological therapy in early arthritis: overtreatment or the way to go? Arthritis Research & Therapy. 2007 ;9:211.
-
1阿达木单抗不会降低类风湿性关节炎患者对流感疫苗的应答[J].传染病网络动态,2007(9):3-3.
-
2马喜喜,徐胜前.肿瘤坏死因子拮抗剂治疗类风湿关节炎的研究进展[J].临床内科杂志,2014,31(1):68-70. 被引量:2
-
3刘樱,许珂,张莉芸,高晋芳,马丹,侯建文,范秋玉.大剂量甲泼尼龙冲击治疗强直性脊柱炎髋关节病变疗效观察[J].中国药物与临床,2015,15(10):1464-1466. 被引量:5
-
4孙琳,郎需和,王兆芬,潘秀霞,王增良,王晓东.关节腔注射肿瘤坏死因子拮抗剂联合甲氨蝶呤治疗类风湿关节炎疗效观察[J].中国实用医药,2014,9(18):166-167. 被引量:2
-
5张徐明,刘群,吴頔,于乐,梅寒颖.甲氨蝶呤与依那西普联用对类风湿关节炎患者的临床疗效及安全性分析[J].抗感染药学,2015,12(6):996-998. 被引量:6
-
6郭小清,王爱霞.肿瘤坏死因子拮抗剂的临床应用前景[J].中华内科杂志,1997,36(1):64-65. 被引量:1
-
7阿达木单抗可用于治疗成人类风湿性关节炎[J].世界临床药物,2003,24(7):387-387.
-
8杜莹珏,田真,姚珍,张卓莉.肿瘤坏死因子拮抗剂治疗结缔组织病相关肺间质病变的现状[J].中华风湿病学杂志,2010,14(11):774-776. 被引量:1
-
9陈国阳,张清平,苏松森,陈永旺,苏密龙.肿瘤坏死因子拮抗剂对强直性脊柱炎患者血清相关细胞因子变化的影响及其机制研究[J].现代生物医学进展,2014,14(28):5486-5490. 被引量:6
-
10张挺,李永吉,朱小春.肿瘤坏死因子拮抗剂在类风湿关节炎中的应用进展[J].实用医学杂志,2012,28(4):523-525. 被引量:8