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作为载药系统的聚合物胶束和泡囊的研究 被引量：6

Study on polymersome micelles and niosomes as the vehicle of medicational system
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摘要 聚合物胶束与泡囊均系由两亲性分子在水中自组装形成的药物载体。本文对它们的定义、形成机理、应用特点、载体材料、制备方法等加以讨论,并介绍其应用进展。 Polymersome micelles and niosomes are the medication vehicle composed by amphiphilic block copolymer self-assembling in water, This article mainly discusses their definition, composing mechanism, application characteristics, carrier materials and preparations, and introduces their latest development and application.
作者 陆彬
机构地区 四川大学华西药学院
出处 《河南大学学报（医学版）》 CAS 2008年第1期1-7,共7页 Journal of Henan University:Medical Science
关键词 聚合物胶束 泡囊 表面活性剂 两亲性嵌段共聚物 聚乙二醇 聚合物泡囊 前体泡囊 Polymersome micelle Niosome Surface active agent ABC PEG Polymersome niosome Anterior nisosome
分类号 R94 [医药卫生—药剂学]
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参考文献37

  • 1Mahmud A, Xiong XB, Aliabadi HM, et al. Polymeric mieelles for drug targeting [ J ]. J Drug Target, 2007, 15 (9) :553 -584.
  • 2Kataoka K, Harada A, Nagasaki Y. Block copolymer micelles for drug delivery : design, characterization and biological significance [ J ]. Adv Drug Deliver Rev, 2001,47 ( 1 ) :113 - 1314.
  • 3Torchilin VP. Structure and design of polymeric surfactant- based drug delivery systems[ J]. J Control Rel, 2001,73(2 -3):137-172.
  • 4许向阳,李玲,殷晓进,周建平,霍美蓉.肿瘤靶向载体N-正辛基-N′-琥珀酰基壳聚糖的制备和结构表征[J].中国药科大学学报,2007,38(1):17-20. 被引量：10
  • 5Kohoria F, Yokoyamab M, Sakaia K, Okano T. Process design for efficient and controlled drug incorporation into polymeric micelle carrier systems[ J]. J Control Rel, 2002, 78(1 -3) :155 - 163.
  • 6冯敏,吴伟荣,潘仕荣.萘普生核-壳型共聚物纳米胶束的制备及特性[J].中国药学杂志,2002,37(7):509-512. 被引量：19
  • 7潘仕荣,冯敏.萘普生/聚乙二醇-聚谷氨酸苄酯共聚物纳米胶束[J].中山医科大学学报,2003,24(1):52-57. 被引量：7
  • 8张跃庭,董岸杰,邓联东,元英进.水溶性紫杉醇两亲性共聚物纳米胶束研究[J].化学工程,2005,33(2):39-43. 被引量：13
  • 9Nishiyama N, Kataoka K. Polymeric micelle drug carrier systems: PEG-PAsp (Dox) and second generation of micellar drugs[ J ]. Adv Exp Med Biol, 2003,519 : 155 - 177.
  • 10Yokoyam M, Fukushim S, Uehar R, et al. Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor[J]. J Control Rel, 1998,50( 1 - 3) : 79 -92.

二级参考文献59

  • 1张强,廖工铁,李明艳.一阶导数光谱法测定聚α－氰基丙烯酸正丁酯毫微粒中硫酸庆大霉素的包封率[J].华西医科大学学报,1994,25(3):353-357. 被引量：4
  • 2姚松年,钟桂荣.卵磷脂有序体中碳酸钙超微颗粒的研究[J].物理化学学报,1994,10(10):950-953. 被引量：14
  • 3张灿,丁娅,平其能.新型两亲性N-辛基-N-PEG化壳聚糖衍生物的合成与表征[J].中国药科大学学报,2005,36(3):201-204. 被引量：9
  • 4Jang SH,Wienties MG,Lu D,et al.Durg delivery and transport to solid tumors[J].Pharm Res,2003,20(12):1337.
  • 5Li YP,Pei YY,Zhou ZH,et al.PEGylated polycyanoacrylate nanoparticles as tumor necrosis factor-alpha carriers[J].J Control Rel,2001,71(3):287.
  • 6Li YP,Pei YY,Zhou ZH,et al.Stealth polycyanoacrylate nanoparticles as tumor necrosis factor-alpha carriers:pharmacokinetics and antitumor effects[J].Biol Pharm Bull,2001,24(6):662.
  • 7Shenderova A,Burke T,Schwendeman S.Stabilization of 10-hydroxycamptothecin in poly(lactide-co-glycolide) microsphere delivery vehicles[J].Pharm Res,1997,14(10):1406.
  • 8Shenderova A,Burke T,Schwendeman S.The acidic microclimate in poly (lactide-co-glycolide) microspheres stabilizes camptothecins[J].Pharm Res,1999,16(2):241.
  • 9Bazile D,Prud' Homme C,Bassoulet MT,et al.Stealth PEG-PLA nanoparticles avoid uptake by the mononuclear phagocytes system[J].J Pharm Sci,1995,84(4):493.
  • 10Gabizon AA.Liposome circulation time and tumor targeting:implications for cancer chemotherapy[J].Adv Drug Deliv Rev,1995,16(2):285.

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河南大学学报（医学版）
2008年 第1期

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