摘要
目的探讨腮腺嗜酸性细胞腺瘤的临床病理学特征。方法对12例腮腺嗜酸性细胞腺瘤进行临床、病理组织学和免疫组织化学观察,并结合文献探讨其临床表现、病理形态及鉴别诊断。结果12例患者平均年龄57.2岁。组织学上见密集的上皮肿瘤细胞片块状分布,瘤细胞圆形或多边形、体积大、胞浆内充满嗜伊红颗粒,胞核圆或卵圆形,核小深染。Vimentin、Actin、S-100在瘤细胞中均阴性表达;EMA和CK强阳性表达。结论腮腺嗜酸性腺瘤比较少见,多发生于老年人。明确诊断依赖于病理检查,应与多种临床类似病变鉴别诊断。
Objective To describe the clinicopathological behavior of oxyphil cell adenoma of parotid and analyze their immunophenotypes and morphological features. Methods With review of the literatures, histopathology, clinical data and immunohistochemistry was used to investigate the clinical appearance, pathological features and differential diagnoses in 12 cases with oxyphil cell adenoma of parotid. Results The tumor cells were oval or polygonal, with abundant, eosinophilic cytoplasm. Immunohistochemistry showed reactivity for EMA, CK, but negative for Vimentin, Actin, S-100 in tumor cells. Conclusions Oxyphil cell adenoma of parotid is a rare type tumor. The definite diagnosis of this disease depends on pathological examination, it should be differentiated from other parotid neoplasms.
出处
《肿瘤基础与临床》
2008年第2期164-165,共2页
journal of basic and clinical oncology
关键词
嗜酸性细胞腺瘤
腮腺肿瘤
免疫组化
oxyphil cell adenoma
parotid neoplasms
immunohistochemistry
