青岛与长沙地区成年女性多部位骨密度的比较

Comprise the difference of bone mineral density reference databases for multiple skeletal regions in women between in Qingdao and Changsha areas

目的通过建立不同厂家双能X线吸收法骨密度仪(DXA)之间的数据换算关系,比较青岛与长沙地区成年女性骨密度(BMD)差异及影响因素。方法选择25～35岁健康成年女性30人分别在Challenger及Holigic QDR4500型DXA上测得BMD值,通过直线相关与回归分析分别计算出腰椎(L2～L4)正位和左侧髋部(股骨颈、大转子、Ward三角区)6个骨骼区域的BMD换算公式,并进行两地区骨密度数据库的比较。结果①Challenger与Holigic QDR4500型DXA之间的骨密度测定数据显著相关,存在线性关系。②校正之前,青岛地区女性髋骨BMD几乎无一例外地高于长沙地区;校正之后两地区骨密度无显著性差别。结论BMD测定受很多因素影响,除地域、性别、生活习惯和BMI外,DXA仪器本身也是很重要的影响因素。

Objective To comprise the difference and effectors of bone mineral density （BMD） reference databases of multiple skeletal regions in women between in Qingdao and Changsha areas in China. The aim is to find the way which could share the different databases from the varied type dual-energy X-ray absorptiometries （DXAs）. Methods 30 healthy women （age 25 - 35y） were selected and had their BMD measured by the different DXAs （Challenge and Hologic）, Then we found the emendation formula from the two varied DXAs. Finally we comprised the the different BMD databases from Qingdao and Changsha areas respectly. Results The BMD data was shown the significant relationship between Challenge and Hologic DXAs. There is significant difference of BMD between both areas, especially in the hip regions Qingdao women are higher than Changsha. area before data emendation. In fact the BMD databases of the both areas showed no significant difference after emendation. Conclusion The effectors of measuring BMD include region, diary habits, sex, BMI, especially the types of the measuring equipments.