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成骨细胞特异性转录因子Osterix的研究进展 被引量：5

Development of the research of osteoblast special transcription factor Osterix
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摘要 Osterix是目前所发现的调节成骨细胞分化的重要转录因子之一,在各种研究中其表达水平被作为成骨细胞分化程度的标志,其发现为人们进一步阐明骨代谢过程,特别是骨质疏松及其他骨病的机制提供了帮助,笔者将对近5年来关于此基因的研究作一综述。 Osterix is one of the most important transcription factors modulating osteoblast differentiation found by now. Its expression is considered to be the marker of the osteoblast differentiation. The research about it will help people to illuminate the mechanism of the bone metabolism, especially the mechanism of the bone disease like the osteoporosis. This article will review the research of this gene in recent 5 years.
作者 徐鹏程 王宝利 邱明才
机构地区 天津医科大学总医院 天津医科大学内分泌研究所
出处 《中国骨质疏松杂志》 CAS CSCD 2008年第4期294-297,共4页 Chinese Journal of Osteoporosis
关键词 OSTERIX 转录因子 骨代谢 Osterix Transcription factor Bone metabolism
分类号 R589.5 [医药卫生—内分泌]
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  • 1Lee MH, Kwon TG, Park HS, et al. BMP-2-induced Os- terix expression is mediated by Dlx5 but is independent of Runx2 [ J ]. Biochem Biophys Res Commun, 2003, 309( 3 ) : 689-694.
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引证文献5

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中国骨质疏松杂志
2008年 第4期

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