摘要
目的探讨人参水提物对阿霉素所致心脏损伤的保护作用．方法50只Wistar大鼠随机分3组：对照组（NS组，10只）、阿霉素组（ADR组，20只）、阿霉素＋人参水提物组（ADR＋G，20只）．13d后在光镜下观察心肌细胞病理形态学变化，检测心肌ATP含量．结果光镜下ADR＋G组心肌损害程度较ADR组轻，ADR＋G组心肌ATP含量明显高于ADR组（P〈0．01）．结论人参水提物对阿霉素所致大鼠心肌损伤有明显的保护作用．
Objective To study the protective effects of water extracts from Ginseng on myocardium injury caused by adriamycin （ADR） in rats. Methods Fifty Wistar rats were randomly divided into three groups：control group, ADR group and ADR ＋ G group. ATP in the sera and myocardium were detected and the histopathological study was performed under light microscope. Results The extent of the myocardial injury in ADM ＋ G group was not as significant as that in the ADR group. ATP in the sera and myocardium in ADR ＋ G group were significantly higher than that of ADR group （ P 〈 0.01 ）. Conclusion The water extracts from Ginseng has obvious protective effects on myocardial injury caused by ADR in rats.
出处
《北华大学学报（自然科学版）》
CAS
2008年第2期135-137,共3页
Journal of Beihua University（Natural Science）
关键词
人参水提物
阿霉素
心肌损伤
Water extracts from Ginseng
Adriamycin
Myocardium injury
