鼻咽癌放疗后放射性脑病的MRI表现

MRI features in radiation encephalopathy(RE) following radiotherapy for nasopharyngeal carcinoma

目的:探讨鼻咽癌放射治疗后放射性脑病的MRI表现。方法:分析31例经病理证实鼻咽癌放射治疗后,放射性脑病MRI的T1WI及T2WI和增强表现及临床表现。结果:放射性脑病的临床表现为头痛、头晕、视力障碍、肢体麻木、无力或瘫痪及颅神经损伤症状。MRI显示大脑及脑干内斑片状改变,自旋回波T1WI病灶呈低或等信号,自旋回波T2WI呈等高混杂信号。增强扫描病灶区无强化者5例,斑点状强化者2例,不规则花环状强化者24例。占位效应与病灶大小不相称。12例复查,2例病灶消失,8例病灶形态及位置无变化。2例病灶增大。结论:MRI可显示放射性脑病的特征,是一种有效的检查方法。

Objective：To study MRI featueres in radiationencephalopathy （RE） following radiotherapy for nasopharyngeal carcinoma. Methods： MRI findings and chinical symptoms in 31 patients with RE after radiotherapy for nasopharyngeal cancer were reviewed. Results： Chinical symptoms of RE included headache, dizzy, vision hinder, weakness or paralysis in the limbs and symptoms of damaged nerves. All lesions appeared hypo - or iso - intense on spin echo（SE）T1 -weighted images and inhomogeneous and mixed hyper-and iso-intense on T2 -weighted images. The enhancement patterns included irregular ring in 24 patients, spotty in 2 and no enhancement in 5 patients. Mass effect was minimal in all patients. On follow- up MRI,the lesons disappeared in 2 patients,did not change in size and shape in 8 patients and enlarged in 2 patients. Conclusion： MRI could demonstrate the characteristic findings of RE. It is an effective method.