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调控组蛋白乙酰化水平抑制膀胱癌细胞机理的研究进展 被引量：1

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摘要 几乎人类每一类肿瘤的发生都与细胞组蛋白去乙酰化水平异常,RB/E2F细胞周期调控通路被打乱,p21waf/cif1转录被抑制有关。p21waf/cif1是细胞增殖周期中极其重要的周期调控蛋白,对肿瘤增殖有关键的抑制作用。以组蛋白的调控为切入点,以RB和p21waf/cif1为枢纽,研究细胞增殖周期抑制膀胱癌细胞增殖的机理。
作者 夏昕晖 何莉 戴福宏 钟甘平
机构地区 广东医学院附属福田医院泌尿外科
出处 《现代肿瘤医学》 CAS 2008年第5期871-873,共3页 Journal of Modern Oncology
基金 深圳市科技计划项目(编号:200404174)
关键词 组蛋白 组蛋白乙酰化水平 膀胱癌
分类号 R737.14 [医药卫生—肿瘤]
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共引文献12

同被引文献31

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现代肿瘤医学
2008年 第5期

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