Barrett食管色素内镜与组织学的一致性观察

Clinical observation on consistency in diagnosis of Barrett's esophagus through pigment endoscope and its histological findings

目的探讨Barrett食管在色素内镜下与组织学的一致性研究,揭示色素内镜在诊断Barrett食管的优越性。方法对125例临床诊断为食管病变的患者分为常规内镜组和色素内镜组,常规内镜组在齿状线2cm以上病变处取活检,色素内镜组用2%Lagol’s液进行染色,根据染色发现的病变取活捡,分别进行组织病理学比较。结果色素内镜组的敏感性和漏诊率分别为73%、27%,常规内镜组为48%、52%,两组比较差异有显著性。结论色素内镜在Barrett食管的诊断和组织学较常规内镜有较好的一致性,且方法简单、实用。

Objective To explore the consistency of manifestation of Barrett＇s esophagus under the pigment endoscope with its histological findings.Methods 125 cases diagnosed as affections of esophagus were divided into two groups ： one using the ordinary endoscope and the other using the pigment endoscope. In the ordilnary endoscope group, the biopsy was taken from the part of pathological changes 2cm above the dentate line; in the pigment endoscope group, the affected part was dyed with 2% Lagol＇s fluid and taken biopsy from the affections through dying, then comparison was made with histopathologic findings. Results The sensibility and rate of missed diagnosis in pigment endoscope group were 73 % and 27 % respectively while in the ordinary endoscope group , they were 48 % and 52%. Thus there was noticeable difference between the two groups. Conclusions The pigment endoscope has a relatively better consistency in the diagnosis of Barrett＇s esophagus with histological findings, therefore is an uncomplicated and practical examination.