结核性胸膜炎胸液体外凝固时间与胸膜肥厚及粘连形成的关系探讨

The relationship of clotting time of pleural effusion body- outside with the developing of pleural thickness and adhesion in tuberculous pleurisy

目的 探讨结核性渗出性胸膜炎胸液体外凝固时间与胸膜肥厚、粘连的关系。方法 216例初治单纯性渗出性胸膜炎患者按胸液体外凝固时间从短到长分为A、B、C3组，入院后第1次胸穿时测定胸液体外凝固时间和纤维蛋白原含量测定，在治疗15d时测量胸膜厚度，评估胸膜粘连情况。结果 组间胸液纤维蛋白原含量；A组与B组比较，t=2．10，P〈0．05；A组与c组比较，t=4．07，P〈0．01；B组与C组比较，t=2．08，P〈0.05。组间胸膜肥厚度：A组与B组比较．t=2．19，P〈0．05；A组与C组比较，t=2．96，P〈0．01；B组与C组比较，t=2.07，P〈0．05。组间胸膜粘连：A组与B组比较，X^2=1．09，P〉0．05；A组与c组比较，X^2=7．56，P〈0．01；B组与C组比较，X^2=4．27，P〈0．05。结论 胸液体外凝固时间与纤维蛋白原含量、胸膜肥厚度与胸膜粘连具有相关性。

Objective To investigate the relationship of cloting time of plerual tuberculous exudative pleurisy with pleural thickness and adhesion. Methods Two hundred and sixteen cases of primary tuberculous pleurisy were divided into three groups（ A 、B 、C ）by length of clotting time of pleural effusion body - outside. The clotting time of pleural effusion body - outside and the fibrinogen concentration were measured in the first thoracentesis. Pleural thickness were measured and the incidence rates of pleural adhesion were assessed in the fifteenth day of the course of treatment. Results The fibrinogen concentration：there were differences between group A and group B,group A and group C ,group B and group C（ t = 2.10, P 〈 0.05 vs t =4.07, P 〈0.01 vs t =2.08, P 〈0.05）. The pleural thickness：there were differences between group A and group B,group A and group C,group B and group C（ t =2.19, P 〈0.05 vs t =2.96, P 〈0.01 vs t = 2.07, P 〈0. 05） ;The incidence rates of pleural adhesion：there was no difference between group A and group B （ X^2 = 1.09, P 〉 0.05 ） ; there was significant difference between group A and group C （ X^2 = 7.56, P 〈 0. 01 ） ; there was difference between group B and group C （ X^2 = 4.27, P 〈 0.05 ）. Conclusion There were relativity in the clotting time of pleural effusion body - outside and the fibrinogen concentration and the pleural thickness and the incidence rates of pleural adhesion.