高尿酸血症与冠心病危险因素关系的探讨

A Study of Relationship between Hyperuricemia and Risk Factors of Coronary Disease

目的:探讨高尿酸血症与血压、脂代谢紊乱、血糖等冠心病危险因素的关系。方法:收集1 768例患者分为高尿酸组及正常尿酸组,将各种临床资料进行分析。结果:高尿酸血症的患病率为19.5%。血尿酸高于均数组,男性更多、更胖,收缩压和舒张压增高,甘油三酯升高,血糖更高。男性、腰围、舒张压、甘油三酯、血糖是预测血尿酸升高的主要因素。结论:血尿酸水平的升高与肥胖、脂代谢紊乱、血压升高、糖尿病密切相关,高尿酸血症是冠心病的危险因素之一,可能成为预测冠心病严重程度的生化指标。

Objective. To study the relationship between hyperuricemia and the risk factors of coronary disease like hypertension, disturbance of cholesterol and diabetes mellitus, etc. Methods： 1 768 patients were collected and classified into hyperuricemia group and normal uric acid group. Clinical materials collected were analysed. Results： The morbidity of hyperuricemia was 19. 5%. Most of hyperuricemia the patients were fatter male person, in which the systolic and diastolic blood pressure, glyceride and blood sugar were higher than that in normal person. Male person, waistline, diastolic blood pressure,glyceride and blood sugar are the main factors for forecasting hyperuricemia. Conclusion： The elevation of the level of the blood uric acid has a close relationship with the obesity, disturbance of cholesterol, hypertension and diabetes mellitus. Hyperuricemia is one of the risk factors of the coronary disease, and maybe becomes a biochemical index for forecasting the severity of coronary disease.