布地奈德、沙丁胺醇雾化吸入治疗儿童哮喘急性发作的疗效观察

Clinical Effect of Budesonide and Ventolin Inhalation in Treating Childhood Acute Asthma Outbreak

目的：观察布地奈德、沙丁胺醇雾化吸入对儿童哮喘急性发作的临床疗效。方法；将136例哮喘患儿随机分为两组，对照组64例，采用氨茶碱、琥珀酸氢化可的松等静滴，解痉、平喘及吸氧等对症治疗，合并感染者使用抗生素；观察组72例，在对照组治疗的基础上加用布地奈德、沙丁胺醇雾化吸入，每日3次，每次5～10min。结果；观察组的主要临床表现恢复正常的时间较对照组短，控制率较高，两组差异均有显著性（P〈0．01）。结论；布地奈德、沙丁胺醇雾化吸入可作为治疗儿童哮喘急性发作的有效方法。

Objective：To observe the clinical effect of budesonide and ventolin inhalation in treating childhood acute asthma outbreak. Methods.. 136 children suffered from asthma were divided into two groups. In the control group （64 cases） aminophylline and hydrocortisone were dripped intravenously, and such measures were taken, as relief of bronchiospasm, oxygen inhalation, and antibiotics were included, if necessary. While the other 72 children（observed group） were treated with budesonide and ventolin inhalation 3 times per day and 5-10 minutes each time, besides those treatments of control group. Results： The clinical symptoms of the observed group disappeared more quickly than that of the control group, and the difference has statistical significance（P〈0. 01） Conclusion： Budesonide and ventolin inhalation is an effective therapy for asthma outbreak.