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奥美拉唑对阿司匹林抗栓治疗影响的临床观察 被引量:8

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摘要 目的:观察奥美拉唑对阿司匹林抗栓治疗的影响。方法:对首次进行抗栓治疗的心脑血管疾病住院患者96例,随机分为两组,对照组给予阿司匹林100mg,1次/d;治疗组在阿司匹林治疗的基础上,给予奥美拉唑20mg,1次/d。1个疗程为10d。结果:治疗组出现胃肠道症状4.2%,对照组33.3%,治疗组出现胃肠道症状明显少于对照组(P<0.05),治疗后门诊或电话随访3个月,治疗组阿司匹林使用率85.4%,不规范用药24.3%;对照组阿司匹林使用率52.1%,不规范用药28.0%。治疗组阿司匹林使用率明显高于对照组(P<0.05),两组不规范用药无显著性差异(P>0.05)。结论:奥美拉唑能有效预防和减轻阿司匹林对老年心脑血管患者胃黏膜损害,并且能提高患者药物依从性。
机构地区 解放军
出处 《陕西医学杂志》 CAS 北大核心 2008年第4期434-435,共2页 Shaanxi Medical Journal
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  • 1胡大一,孙艺红.美国胸科医师协会抗栓和溶栓治疗指南简介(1)[J].中国医药导刊,2005,7(1):62-66. 被引量:11
  • 2郑秋甫.第二篇:疾病篇 冠心病(一)[J].解放军保健医学杂志,2005,7(2):124-126. 被引量:3
  • 3[3]European Society of Cardiology.Expert consensus document on the use of antiplatelet agents.The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European Society of Cardiology[J].European Heart J.2004,25:166-181
  • 4[4]陈纪林.抗血小板治疗的规范化问题[N].中国医学论坛报.2005,6
  • 5Antithrombotic Trials, Collaboration. Prevention of death, myocardial infarction end stroke by antiplatelet therapy in high risk patients. BM J, 2002; 324;71 ~ 86.
  • 6Bertrand MF, Simoons ML, fox KA, et al. Management of acute Coronary syndromes: acute coronary synchromesh without persistent ST segment elevation recommendations of the Task Force of the European Society of Cardiology.Eur Heart J, 2000;21: 1406~1032.
  • 7Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA guidelines for the management of patients with unstable angina and non - ST - segment elevation myocardial infarction. A report of the American College of Cardiology American Heart Association Task force on practice Guidelines (Committee on Management of Patients with Unstable Angina ) J Am Coll Cardiol, 2000;36:970 ~ 1062.
  • 8TDRS Investigators. Aspirin effects on mortality and morbidity in patients with diabetes mellitus Early treatment diabetic retinopathy study report 14. JAMA,1992;268: 1992~1300.
  • 9Hansson L, Zanchetti A, Carruthers SG, et al. Effects of intensive blood pressure lowering and low - dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomized trial.Lancet, 1998;351: 2075~2195.
  • 10Filling B, Schiele R, Gitt AK, et al. Characterization and clinical course old patients not receiving aspirin for acute myocardial infarction: Results form the MITRA and MIR studies. Am Heart J, 2001; 141: 200 ~ 205.

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