盐酸万古霉素和去甲万古霉素用药分析

ANALYSIS OF DRUG USE OF VANCOMYCIN HYDROCHLORIDE AND NORVANCOMYCIN

[目的]了解我院临床万古霉素类药物的使用情况,评价其用药合理性。[方法]采用回顾性调查方法,分别将2007年1～5月我院住院病人应用万古霉素类药物—去甲万古霉素(华北制药)、万古霉素(稳可信)的病例共64份进行药物合理性利用分析。[结果]64份病例中合理用药10例(15.625%),基本合理用药6例(9.375%),不合理用药48例(75%)。[结论]目前万古霉素类药物的临床应用有所放宽,不合理用药也随之增加。提高合理用药水平有助于减少耐药菌株的出现,应采取措施,严格适应证,保护该类药物的使用寿命。

[ Objective ] To investigate the clinical utilization status of vaneomycin in our hospital, and to evaluate the rationality of drug use. [ Methods] By retrospective survey method, 64 patients treated by vaneomycin - norvancomycin （North China Pharmaceutical） and vancomycin （stable credible） in our hospital from January 2007 to May 2007 were collected to analyze the rational utilization of drug. [Results] Out of 64 patients, 10 patients with rational utilization of drug, 6 patients with basic rational utilization of drug and 48 patients with non-rational utilization of drug accounted for 15.625%, 9.375% and 75%, respectively. [ Conclusion] With the liberalization of clinical utilization of vancomycin, the non-rational utilization of drug is increasing. To improve the rational use of drug could be helpful to decrease the drug resistant strain, and effective measures should be taken to strengthen the indication so as to protect the useful life of vancomvcin.