2-胺基(芳氧基)-5，8，9-三甲基噻吩并吡啶并[4，3-d]嘧啶-4(3H)-酮的合成和生物活性

Synthesis and Biological Activities of 2-(Amino/aroxy)-5,8,9- trimethylthieno[3',2'∶5,6]pyrido[4,3-d]pyrimidin-4(3H)-one Derivatives

利用串联Aza-Wittig法合成了两类共计16个未见文献报道的噻吩并吡啶并嘧啶类化合物,通过IR,1HNMR,EI-MS,元素分析等方法对所合成的化合物进行了结构表征,化合物II-1还通过了X单晶衍射的进一步确证.并初步测定了所合成化合物的杀虫、杀菌和除草活性.结果表明:所测化合物的杀虫活性较差,但大部分化合物具有一定的除草活性和良好的杀菌活性.

A series of new 2-（amino/aroxy）-5,8,9-trimethylthieno[3＇,2＇ ： 5,6]pyrido[4,3-d]pyrimidin-4（3H）- one derivatives have been designed and synthesized via an aza-Wittig reaction and structually confirmed by elemental analysis, IR, ^1H NMR, EI-MS spectra, and compound Ⅱ-1 by X-ray diffraction analysis. Their biological activities were also researched and many of them showed good fungicidal and herbicidal activities to some extent.