超选择肾动脉化疗栓塞治疗老年性晚期肾癌

Treatment of senile patients with advanced renal carcinoma with superselective renal arterial chemoembolization

目的探讨超选择肾动脉化疗栓塞治疗老年性晚期肾癌的疗效及意义。方法对我科采用超选择肾动脉化疗栓塞治疗的37例老年(年龄70～77岁,平均74岁)晚期肾癌患者的临床资料及随访情况进行回顾性分析。结果栓塞治疗后,所有患者症状与体征不同程度减轻甚至消失,如血尿消失,食欲、体重增加。术后1a、2a和3a生存率分别为59%、54%和22%。结论超选择肾动脉化疗栓塞是老年性晚期肾癌首选的姑息疗法,碘油药物乳剂和明胶海绵颗粒是肾癌较佳的栓塞材料。

Objective To evaluate the efficacy of superselective renal arterial chemoembolization（SRACE） in the treatment of senile patients with advanced renal carcinoma（ARC） . Methods Clinical and followed-up results of 37 senile patients （aged70 -77 years; mean age, 74 years）who underwent SRACE for ARC were analyzed retrospectivcly. Results Afrer the operation of SRACE, all the patients whose clinical symptoms and signs were more or less relieved or even disappeared, for example, disappearance of hematuria and increase of appetite and body weight. The survival rate of this group patients at 1-, 2-and 3 year after the operation of SRACE was 59%, 54% and 22%, respectively. Condusion SRACE can be taken as an effective palliative treatment for senile patients with ARC, while the lipiodol-medication emulsion and gelatin sponge are effective embolization agents for renal carcinoma.