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胶质瘤干细胞研究的新观点 被引量：5

New Concepts in Glioma Stem Cell Research
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摘要 已经有许多证据表明,多种类型的胶质瘤组织中存在一小群具有干细胞特性的细胞,称为胶质瘤干细胞(glioma stem cells,GSCs)。它与胶质瘤的发生发展密切相关,并由此提出了GSCs假设。但随着研究的深入,在深层次问题上出现了争议,并由此产生了一些新的观点。本文结合笔者的工作谈一些看法。 There are evidences that in many gliomas, a minority cell population with stem cell properties （glioma stem cells, GSCs） is responsible for the maintenance and growth of the tumor. But there are lots of controversies among the details of glioma stem cell hypothesis. In this perspective article we will summarize the others and ours experimental evidence that illustrates the characteristics of GSCs and discuss its implications for future gliomas research.
作者 陈骅 黄强
机构地区 南京医科大学附属南京市第一医院神经外科 苏州大学附属第二医院神经外科
出处 《中国神经肿瘤杂志》 2008年第1期1-4,共4页 Chinese Journal of Neuro-Oncology
关键词 胶质瘤干细胞 神终千细朐 CD133 信号通路 Glioma stem cells Neural stem cells CD133 Signal pathway
分类号 R739.41 [医药卫生—肿瘤]
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参考文献1

二级参考文献15

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  • 2张全斌,黄强,兰青.脑肿瘤干细胞的热点问题及研究进展[J].中华医学杂志,2005,85(26):1868-1870. 被引量：21
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共引文献17

同被引文献62

  • 1朱玉德,季晓燕,黄强,张全斌,董军,王金鹏,王爱东,兰青.人脑胶质瘤干细胞初步研究[J].中华神经外科杂志,2007,23(2):127-130. 被引量：30
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引证文献5

二级引证文献10

中国神经肿瘤杂志
2008年 第1期

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