脑动脉粥样硬化斑块的分布及其临床意义

Clinical Significance for the Distribution of Cerebral Atherosclerosis

目的:为我国研究脑血管疾病提供脑动脉粥样硬化形态学基础。方法:全脑血管造影检查结果阳性患者259例,对其斑块的发生部位以及与高血压、糖尿病及高血脂状态等合并症的关系进行分析。结果:脑动脉粥样硬化的好发部位主要为颈内动脉起始部和椎动脉起始部,其次为大脑前动脉、大脑中动脉和锁骨下动脉。27.6%合并糖尿病,24.1%合并高脂血症,58.7%合并高血压。结论:脑动脉粥样硬化是多因素疾病,脑动脉粥样硬化斑块以多病变、双侧共同病变及复杂病变为主。

Objective： To provide the morphological evidence of cerebral atherosclerosis （CAS） for investigating cerebrovascular disease （CVD）. Methods：259 cases with CAS were confirmed by aortocranial angiography. The relationship between the locations of CAS and complications such as hypertension, diabetes, hyperlipemia and et al, was .analyzed retrospectively. Results：The predilection sites of CAS are the originated regions of internal carotid artery and vertebral artery; next are anterior cerebral artery, middle cerebral artery and subclavian artery. 27.6% of the patients with CAS were complicated by diabetes, 24. 1% by hyperlipemia, and 58.7% by hypertension. Conclusion： The CAS is a disease affected by multiple factors, its plaques predominantly present as two or more lesions, hibateral lesions and complicated pathological changes.