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经股动-静脉体外膜肺氧合在心肺复苏中的实验研究 被引量:3

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摘要 目的探讨经股动-静脉体外膜肺氧合(ECMO)在心肺复苏中对循环和氧供给的作用及其对脑氧代谢和能量代谢的影响。方法12只猪随机分成2组,电致颤法诱导心脏骤停,8min后开始复苏。常规心肺复苏组行常规心肺复苏。ECMO组在常规心肺复苏5min基础上加用ECMO,观察猪的血流动力学,血气分析,脑氧代谢等指标。结果ECMO组在转机后各时间点平均动脉压、心脏灌注压、心排量、动脉血氧分压、血氧饱和度、脑氧耗/脑糖耗比值明显高于常规心肺复苏组(P<0.05);动脉血二氧化碳分压低于常规心肺复苏组(P<0.05)。结论ECMO可维持心脏骤停心肺复苏后猪稳定的血流动力学与氧供给,改善脑氧代谢和脑能量代谢,减轻脑损害。
出处 《南方医科大学学报》 CAS CSCD 北大核心 2008年第4期521-523,共3页 Journal of Southern Medical University
基金 广东省社会发展领域科技计划项目(63119) 广东省医学科研基金(A2003858)
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同被引文献43

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