小肠系膜滤泡树突状细胞肉瘤1例报告并文献复习

Small Mesenteric Follicular Dendritic Cell Sarcoma:One Case Report And Literature Review

目的:探讨小肠系膜滤泡树突状细胞肉瘤的病理组织学与免疫组化特点,提高对此病的认识。方法:运用组织病理学和免疫组化观察小肠系膜滤泡树突状细胞肉瘤的特点,并复习相关文献加以分析总结。结果:瘤细胞呈弥漫性排列,细胞境界不清,呈"合体细胞"样,核椭圆形,染色质淡,空泡状或点彩状,有小核仁,并见病理性核分裂;瘤细胞CD21、CD35、CD68、S-100、LCA、CD56均阳性,CD117局灶阳性,Ki-67增殖指数为20%,HHF35、CD34、CD30、CK、CD20、CD3、CD43均阴性。结论:小肠系膜滤泡树突状细胞肉瘤是一种少见的中度恶性肿瘤,诊断主要依据组织病理学和免疫组化标记。

Objective：To explore the small mesenteric follicular dendritic cell sarcoma（FDCS） of the histopathological and immunohistochemical characteristics, raising awareness of this disease. Methods：Histopathologic and immunohistochemical observation of small mesenteric follicular dendritic cell sarcoma characteristics, and related literature re view were analyzed and summarized. Results：Diffuse tumor cells were arranged, cell realm unclear, in a ＂Fitness cell＂ kind,nuclear oval,chromatin desalination, or cavitation-point color shaped, small nucleoli ,and see pathological karyokinesis ; tumor cells CD21、CD35、CD68、S-100、LCA、CD56 were positive ,CD117 focal positive, Ki-67 proliferation index for the 20 percent, HHF35,CD34,CD30, CK,CD20,CD3,CD43 were negative. Conclusion：The small mesenteric follicular dendritic cell sarcoma is a rare malignancy moderate, mainly based on histopathological diagnosis and immunohistochemieal markers.