保护性毛刷在肺部重症感染中应用价值的探讨

Protective Specimen Brush via Fiber Ptic Bronchoscope in Severe Pneumonia:Its Application Value

目的了解保护性毛刷在重症肺部感染中的应用价值。方法对57例临床诊断为重症肺部感染并机械通气的患者,经气管插管或气管套管作纤维支气管镜检查,以保护性毛刷采集下呼吸道病灶部位标本并进行细菌定量培养;临床根据细菌培养及药敏结果调整抗感染药物。结果保护性毛刷标本培养阳性率78.95%、敏感性97.73%、特异性84.62%;而且,在标本采集前后,患者的生命体征没有显著性变化;培养结果阳性患者治疗有效率达91.23%。结论经纤维支气管镜引导行保护性毛刷检查对重症肺部感染患者安全可靠,有较高的临床实用价值。

OBJECTIVE To understand the application value of protective specimen brush（PSB）in severe pneumonias.METHODS Fifty seven cases diagnosed as severe pneumonia were admitted into the group.The specimens were sampled via the fiberoptic bronchoscope（FOB）and the PSB and then were done bacteria quantitative culture（QC）.According to these,we adjusted antibiotics.RESULTS With the PSB and bacteria QC technologies,45 strains were detected in 57 cases,with a positive rate of 78.95%.In the progress of operating FOB-PSB examination,patients life signs didn＇t change significantly.FOB-PSB＇s sensitivity and specificity were about 97.73% and 84.62%,respectively.The therapy efficiency rate was 91.23%.CONCLUSIONS It is a good choice to use the PSB for sampling in severe pneumonia via fiberoptic bronchoscope.