暂短性脑缺血发作(TIA)中医辩证与脂蛋白(a)关系的初步理论研究

Short ischemic attack(TIA) and the Chinese dialectical Dan White resin(a) the relationship between the theoretical research

目的:研究暂短性脑缺血发作(TIA)中医辩证与脂蛋白(a)关系。方法:依据1986年中华医学会第二次全国脑血管病学术会议制订的"短暂性脑缺血发作"诊断标准诊断TIA患者180例,对照组选自体检无心脑血管、肝、肾疾病、糖尿病及高血脂症的健康人共50例。参照TIA中医辩证标准分组统计为3型:单纯性标实型组,单纯本虚型组,虚实夹杂型组,实验室检查血液脂蛋白LP(a),统计学处理:LP(a)为正偏态分布,对数变换后用显著性t检验。LP(a)检测数据以均数标准差(X±S)表示。结果:不同类型组患者血清LP(a)浓度的变化:TIA组(0.27±0.15),对照组(0.18±0.12),与对照组比较P<0.05。单纯本虚型组(0.20±0.14),单纯性标实型组(0.27±0.15),虚实夹杂型组(0.25±0.13),后二者与对照组比较P<0.01,与单纯本虚型比较P<0.05,两组差异有极显著意义。结论:TIA3种中医证型其血清LP(a)浓度存在差别。以单纯标实证型组异常升高显著,虚实夹杂型组平均LP(a)浓度也明显高于对照组,而单纯本虚组LP(a)改变不显著。3组不同中医证型之间比较显示,单纯标实组其LP(a)浓度很显著高于单纯本虚组。血清LP(a)浓度升高这一改变属于中医病机中的一种实邪,但究竟属于标实中的痰浊之邪,还是气滞血瘀之邪,有待进一步研究。

Objective To study the short isehemic attack （TIA） and the Chinese dialectical Dan White resin （a） relationship. Methods The 1986 Chinese Medical Association Second National Symposium on cerebrovascular diseases of the ＂transient ischemic attack＂ diagnostic criteria for diagnosis of patients with TIA 180 cases,From the control group medical unmotivated cerebral vascular, liver and kidney disease, diabetes and high blood lipids of the total 50 cases of healthy people. TIA Chinese dialectical reference standard packet statistics for the three. Superscript-group is simple, simply type the virtual group, the strength of Inclusion Group, laboratory tests, blood lipid Dan White LP （a） , statistically： LP （a） the distribution is skewed, with a few notable transformation of the t test. LP （a） detection are few data to the standard deviation （X ± S） .Results The serum of patients with different types Group LP （a） concentration changes： TIA group （0,27 ± 0.15） and the control group （0.18 ± 0.12） , compared with the control group P 〈0.05. The virtual-only group （0.20 ± 0.14） , it is simple superscript type group （0.27 ± 0.15） ,Inclusion of strength （0.25 ± 0.13） , the latter two with the control group, P 〈0.01, and the simple comparison of the virtual P 〈0.05 difference between the two groups is very significant.Conclusion TCM TIA3 kinds of serum LP （a） concentration difference. Empirical simply type superscript to abnormal increase significantly, the inclusion of group average strength LP （a） concentrations were higher, and this simply false Group LP （a） did not change significantly.TCM three groups of different comparison between that group is the only standard LP （a） concentration was significantly higher than that of the virtual group. Serum LP （a） the change of concentration of Chinese machine is a heresy, but what is the real standard of phlegm evil, or the evil Qichixieyu pending furtber study.