甲状腺Hürthle细胞肿瘤15例诊治分析

Diagnosis and treatment for Hürthle cell tumor of thyroid gland:a report of 15 cases

目的总结分析甲状腺Hürthle细胞肿瘤诊治经验。方法回顾性分析东南大学附属中大医院2002-2006年收治的15例甲状腺Hürthle细胞肿瘤的临床病理资料。结果病人均以发现颈部包块就诊。女性14例。术前甲状腺功能检查均正常,B超、ECT无法确诊,细针穿刺发现Hürthle细胞。术中快速冰冻均能确诊。15例中,13例为良性,其中8例行腺叶切除加峡部切除,3例单纯腺叶切除,2例合并甲状腺乳头状癌而行根治术;2例为恶性,均行根治手术。术后随访无复发。结论应充分认识甲状腺Hürthle细胞肿瘤,重视细针穿刺细胞学检查。术中冰冻切片检查对诊断很重要。选择合适的手术方式可使病人获得良好的预后。

Objective To summarize the experience of the diagnosis and treatment of thyroid Hürthle cell tumor. Methods The clinical data of 15 cases of Hürthle cell tumor of thyroid gland admitted between 2002 and 2005 in the Affiliated ZhongDa Hospital of Southeast University were analyzed retrospectively. Results Among 15 cases of Hürthle cell tumor of thyroid gland, 14 cases were female. The most common symptom was solitary thyroid mass. The thyroid function test was normal. Untrasonography and ECT couldnt make a definite diagnosis. Hürthle cells were found by the fine needle aspiration cytology examination. Frozen section could give a definite diagnosis during operation. Thirteen cases were benign tumor. Among them ,8 cases were performed total lobectomy and isthmusectomy, and 2 cases complicated with thyroid papillary tumor were performed lobectomy. Radical resection were performed for 2 cases of malignant tumor. There were no recurrence during follow-up peroid. Conclusion It is important to be familiar with the entity. Frozen section analysis should be required during operation. Choosing appropriate resection method can get a good prognosis.