瑞芬太尼复合丙泊酚静脉麻醉在无痛胃镜检查中的应用

The application of propofol combined with remifentanil in intravenous anesthesia for gastroscopy

目的探讨瑞芬太尼复合丙泊酚静脉麻醉在无痛胃镜检查中的可行性。方法将按美国麻醉医师协会（ASA）体格情况分级Ⅰ～Ⅱ级行胃镜检查的患者100例，随机分为2组：Ⅰ组50例，瑞芬太尼复合丙泊酚麻醉，静脉注射瑞芬太尼0．5μg／kg及丙泊酚1．0mg／kg；Ⅱ组50例，芬太尼复合丙泊酚麻醉，静脉注射芬太尼0．5μg/kg及丙泊酚1．0mg／kg，比较两组患者的苏醒时间、离院时间以及丙泊酚的用量。结果Ⅰ组丙泊酚的用量少于Ⅱ组（P〈0．01），Ⅰ组的苏醒时间短于Ⅱ组（P〈0．01），Ⅰ组的离院时间早于Ⅱ组（P〈0．01）。结论瑞芬太尼复合丙泊酚用于胃镜检查是一种安全、苏醒时间短、离院时间早的麻醉方法，并可减少丙泊酚的用量。

Objective To explore the feasibility and safety of propofol combined with remifentanil in intravenous anesthesia for gastroscopy. Methods Total 100 patients with ASA（ american society of anesthesiologists）Ⅰ - Ⅱ were divided into 2 groups randomly： group Ⅰ （ propofol combined with remifentanil）, group Ⅱ （ propofol combined with fentanyl ）. Results The anesthesia effects of two groups were similar. However, the awake time and the discharge time of group Ⅰ were significantly more shorter than group Ⅱ （P 〈0. 01 ）. Conclusion The propofol combined with remifentanil gives effective anesthesia and better recovery intravenous anesthesia for gastroscopy.