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肝癌患者血浆可溶性血栓调节蛋白及蛋白C的检测及其临床意义 被引量:2

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摘要 目的探讨肝细胞癌(HCC)患者手术前后血浆可溶性血栓调节蛋白(soluble thrombom dulin,sTM)及蛋白C(protein C,PC)水平变化及其临床意义。方法采用双抗体夹心ELISA法对20例肝细胞癌患者手术前后血浆sTM含量进行检测,同时应用发色底物法检测血浆PC活性。结果肝细胞癌患者术前血浆sTM水平明显高于健康对照组(P<0.01),而肝细胞癌患者术前血浆PC水平明显低于健康对照组(P<0.01)。术后血浆sTM水平较术前明显降低(P<0.05),术后血浆PC水平较术前明显升高(P<0.01)。结论肝细胞癌患者存在不同程度的血管内皮细胞损伤及凝血系统的激活,并随手术病情的好转而逐渐改善。
出处 《现代检验医学杂志》 CAS 2008年第2期123-123,共1页 Journal of Modern Laboratory Medicine
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