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基质金属蛋白酶、基质金属蛋白酶抑制剂与心肌重塑 被引量:5

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作者 郭晋爱 蔡毅
出处 《中西医结合心脑血管病杂志》 2008年第4期450-452,共3页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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参考文献7

  • 1Hijova E. Matrix metalloproteinases: Their biological functions and clinical implications[J ]. Bratisl Lek Listy,2005,106(3) : 127 - 132.
  • 2汪砚雨,阎西艴.基质金属蛋白酶在心室重构及充血性心力衰竭中的地位[J].医药论坛杂志,2004,25(11):78-79. 被引量:3
  • 3Batlle M, Perez Villa F, Garcia Pras E, et al. Down - regulation of matrix metalloproteinase - 9 ( MMP - 9) expression in the mycvardium of congestive heart failure patients [ J ]. Transplant Proc, 2007,39 ( 7 ) : 2344 - 2346.
  • 4Fdkin LE, Birks EJ, George R, et al. A quantitative gene expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the mycocardium of patients with deteriorating heart failure requiring left ventricular assist device support[J ]. J Heart Lung Transplant, 2006,25(12) : 1413 - 1419.
  • 5Ahmed SH, Clark LL, Pennington WR, et al. Matrix metallopro teinases/tissue inhibitors of metalloproteinases: Relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease[J]. Circulation, 2006,113 (17) : 2089-2096.
  • 6Mori S, Gibson G, McTiernan CF. Differential expression of MMPs and TIMPs in moderate and severe heart failure in a transgenic model [J]. J Card Fail,2006,12(4): 314-325
  • 7King MK, Coker ML, Jarnes AG, et al. Selective matrix metalloproteinase inhibition with developing heart failure: Effects on left ventricular function and structure[ J]. Circ Res,2003,92 : 177-185.

二级参考文献8

  • 1Spinale FG. Coker ML, Bond BR, et al. Myocardial matrix degradation and metalloproteinase activation in the failing heart : a potential therapeutic target. Cardiovasc Res 2000,46(2) :225-238.
  • 2Spinals FG. Matrix metallproteinases:regulation and dysregulation in the falling heart. Circ Res,2002,90(5) :520-530.
  • 3Siwik DA, Chang DL, Colucci WS. Interleukin - 1 beta and tumor necrosis factor - alpha decrease collagen syntheis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro. Circ Res,2000,86( 12 ) :1259-1265.
  • 4Spinale FG, Coker ML, Heung LJ, et al. A matrixmetallo-proteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure. Circulation 2000,102(16) :1944-1949.
  • 5King MK, Coker ML, Goldberg A, et al. Selective matrix metalloproteinase inhibition with developing heart failure:effects on left ventricular function and structure. Circ Res,2003,92 (2) :177-185.
  • 6Dixon IM, Ju H, Reid WL, et al. Cardiac collagen remodeling in the cardlomyopathic Syrian hamster and the effect of losartan. J Mol Cell Cardiol, 1979,29 (7) : 1837 -1850.
  • 7Sivasubramanian N, Coker ML, Kurrelmeyer KM, et al. Left ventricular remodeling in transgenic mice with cardiac restricted over expression of tumor necrosis factor. Circulation2001,104(7 ) :826-831.
  • 8McElmurray JH 3rd, Mukherjee R, New RB, et al. Angio-tension- converting enzyme and matrix metalloproteinase inhibition with developing heart failure:comparative effects of left ventricular function and geometry. J Pharmacol Exp Ther, 1999,29 (2) :799-811.

共引文献2

同被引文献39

  • 1边素艳.基质金属蛋白酶及其组织抑制因子在心肌梗死后心室重构中的作用[J].现代诊断与治疗,2006,17(1):27-30. 被引量:9
  • 2张运,徐瑞.心肌纤维化——心力衰竭治疗的新靶标[J].中华医学杂志,2006,86(17):1155-1157. 被引量:28
  • 3张艳,方素清,姜凯,宋婷婷.慢性心衰气虚血瘀证大鼠模型的研究初探[J].中国中医药信息杂志,2006,13(8):14-15. 被引量:29
  • 4张美燕,郑兴.基质金属蛋白酶-9在心血管疾病中的研究进展[J].心血管病学进展,2007,28(1):88-91. 被引量:7
  • 5OKADA Y,NARA K,KAWAMURA K.Localization of matrix metalloproteinase 9 (92 kDa gelatinase/type Ⅳ collagenase=gelatinase B) in osteoclasts:Implications for bone resorption[J].Lab Invest,1995,72:311-322.
  • 6AIMES R T,QUIGLEY J P.Matrix metalloproteinase-2 is an interstitial collagenase:Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4 and 1/4 length fragments[J].J Biol Chem,1995,270:5872-5876.
  • 7HAYASHIDA,TSUTSUI H,IKEUCHI M,et al.Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction[J].Am J Physiol Heart Circ Physiol,2003,285:H1229-1235.
  • 8FRANCIS G,SPINALE F G.Matrix Metalloproteinases regulation and dysregulation in the failing heart[J].Cir Res,2002,90:520-530.
  • 9GRAHAM H K,TRAFFORD A W.Spatial disruption and enhanced degradation of collagen with the transition from compensated ventricular hypertrophy to symptomatic congestive heart failure[J].Am J Physiol Heart Circ Physiol,2007,292:1364-1372.
  • 10ARENAS I A,XU Y,LOPEZ-JARAMILLO P,et al.Angiotensin Ⅱ-induced MMP-2 release from endothelial cells is mediated by TNF-α[J].Am J Physiol Cell Physiol,2004,286:C779-784.

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二级引证文献26

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