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HLA-B27与强直性脊柱炎的临床分析

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摘要 目的了解本地区强直性脊柱炎(AS)与HLA-B27的关联性。方法用微量淋巴细胞毒试验对191例确诊为强直性脊柱炎的患者进行HLA-B27抗原检测。结果HLA-B27抗原阳性171例,阳性率90%。抗原阳性组男女比为5.3:1。本病发病年龄多在30岁以内,占71%。患者症状以骶髂关节、髋关节痛为主,常伴晨僵,夜间疼痛加重、活动后减轻。结论对长期不明原因的腰腿痛患者及早检测HLA-B27抗原对AS的诊断帮助很大。
作者 李菲 宋燕华
出处 《医药论坛杂志》 2008年第7期93-94,共2页 Journal of Medical Forum
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