血液灌流抢救重度有机磷农药中毒58例疗效观察

Efficacy of Application of Hemopefusion for the Treatment of 58 Cases Acute Serious Arganic Phosphorus Intoxication

目的:对运用血液灌流抢救重度有机磷农药中毒(ASOPP)的疗效进行观察。方法:将104例ASOPP病人随机分作两组,一为内科常规治疗组(对照组)46例,另一为内科常规治疗+血液灌流组(HP组)58例。观察两组病人的昏迷时间、胆碱酯酶(CHE)恢复时间、阿托品总用量、治愈率、病死率,住院时间等指标差异。结果:与对照组比较,HP组的意识恢复清醒时间短,血清CHE恢复快,阿托品总用量少,住院总时间短(P<0.05)。结论:ASOPP内科常规治疗基础上加用HP治疗可以提高抢救成功率,降低病死率。

Objective： To study the efficacy of Application of hemopefusion （ HP ） for the treatment of Acute Serious organic Phosphorus intoxication （ASOPP）. Method： 104 patients with ASOPP were randomly divided into 2 groups,46 patients accepted traditional treatment（ control group ） ,58 patients were treated with traditional treatment and HP （ HP group ）. Coma period, the dosage of atropine, the time of regaining the vitality of eholinesterase, the time of hospitalization, the rate of fatality between HP group and control group was observed. Result： The coma period, the dosage of atropine , the time of regaining the vitality of eholinesterase, the time of hospitalization and the rate of fatality of HP group were less than those of control group （ P 〈 0. 05 ）. Conclusion： Application of hemopefusion for the treatment of ASOPP can improve the rate of cure and lower the rate of fatality,It is security.