中西医结合治疗急性坏死性胰腺炎

Integrated traditional and western medicine in treatment of acute necrotic pancreatitis

目的探讨中西医结合治疗急性坏死性胰腺炎(ANP)的新方法及手术时机与预后的关系。方法对30例ANP患者的中西医结合治疗与手术时机的选择及并发症的发生率、病死率进行回顾分析。结果早期手术组和中西医结合组死亡率分别为11.5%(10/87),死亡率9.1%(3/33);并发症的再手术率分别为再手术率为28.7%(25/87),21.2%(7/33)。结论ANP的治疗选择是直接影响预后的重要因素,根据ANP自然病理过程应避免在急性期手术,而尽可能地采取中西医结合治疗,度过急性反应期后再处理局限性病灶。

Objective To explore the new method and operative opportunity for treatment of patients with acute necrotic pancreatitis （ANP） and to analyze its prognosis concerning treatment of Integrated Traditional and Western Medicine. Methods The clinical data of 30 patients with ANP were retrospectively analyzed, and the treatment of Integrated Traditional and Western Medicine, choice of operative opportunity, incidence rate and mortality rate of complications were studied. Results The mortality rates of patients in early operation group and Integrated traditional and western medicine treatment group were 11.5 % （ 25/87 ） and 9.1% （ 3/33 ） respectively, the re - operation rates for complications were 28.7% （25/87） and 21.2% （ 7/33 ） respectively. Conclusion The choice of treatment for ANP is the most important factor which can directly influence its prognosis. According to the naturally pathological process of ANP, operation should be avoided in acute stage, and treatment of Integrated Traditional and Western Medicine can be applied as soon as possible, and rehandling localized lesion may be carried out after acute reaction period.