脑脊液正常流动的MRI研究

MRI estimation of cerebrospinal fluid flow in normal volunteers

目的探讨MRI相位对比序列(cinePC)研究和分析脑脊液流动的可能性,并运用该技术对正常志愿者进行分析。方法采用MRIcinePC序列,对正常志愿者进行分析,并测量中脑导水管上下丘之间的横断层面脑脊液的流动速度。结果MRIcinePC序列可清楚地显示心脏周期各个时段各个脑室、脑池和脊髓蛛网膜下腔中脑脊液运动方向的变化,并能对脑脊液流速进行精确地测量。结论MRIcinePC法是一种新型的无创性的检查手段,对脑脊液的流动有很强的敏感性,是一种很有前途的研究手段。

Objective To evaluate the feasibility of the cerebrospinal fluid （CSF） flow measurement by cine phase contrast MRI. Methods Evaluation of intracranial CSF flow was accomplished by the use of periphery gated cine phase contrast MRI technique. Evaluation of CSF flow via phase reconstruction permits a more precise mapping of the intracrauial flow patterns,is sensitive in detecting fluid motion and al- lows calculation of CSF velocity. Results CSF flow within ventricle, cistern, and subarachnod space could be clearly displayed. Calculations of actual fluid velocity within CSF- containing spaces could be obtained from the phase reconstruction images and holds premise for a more accurate analysis of CSF flow. Concluions Cine phase contrast MRI is capable of demonstrating intracranial CSF flow. As a new noninvasive technique, it is really superior to other modalities in studying the flow pattern , direction, speed, and quantity of CSF.