慢性湿疹和皮炎126例不同患病部位斑贴试验结果分析

Clinical Analysis of the Patch test of Different Sick Parts in 126 Cases of Chronic Eczema and Dermatitis

目的:探讨湿疹和皮炎等变态反应性疾病的接触性致敏原及其不同患病部位致敏原的特点。方法:应用"瑞敏牌"斑贴试剂盒检测126例慢性湿疹和皮炎患者接触性致敏原。结果:列前8位的常见致敏原分别是硫酸镍、芳香混合物、硫柳汞、重铬酸钾、对苯二胺、甲醛、对苯类、卡巴混合物;引起面部湿疹和皮炎的致敏原主要为芳香混合物、重铬酸钾、对苯二胺,手部主要为硫柳汞、芳香混合物、重铬酸钾、对苯二胺,躯干、四肢主要为硫酸镍和硫柳汞,脐周主要为硫酸镍。结论:斑贴试验有助于明确慢性湿疹和皮炎患者的接触性致敏原,并发现不同部位皮炎和湿疹常见致敏原的不同。

Objective：To discuss the characteristics of contact allergens in chronic eczema and dermatitis and different sick parts. Methods： One hundred and twenty six cases of chronic eczema and dermatitis were tested with a standardized patchtesting technique （ Rei Min Pal） against contact allergens. Results：Data from these patients showed that the top 8 allergens were as follows： nickel sulfate, fragrance mixture, thimerosal ,kalium bichromicum,P-phenylenediamine, formaldehyde, benzene, carba mixture. The allergens causing eczema and dermatitis of the face were ： fragrance mixture, kalium bichromicum, P-phenylenediamine, those for hands were ： thimerosal, fragrance mixture, kalium bichromicum and P-phenylenediamine,those for trunk and limbs were：nickel sulfate and thimerosal ,and that for navel eczema was nickel sulfate. Conclusion：Patchtesting is helpful in identifing the property of contact allergens in chronic eczema and dermatitis,and there are different allergens in diverse sick parts.