急性脑血管病血清白蛋白、尿素氮、肌酐、血脂的变化及临床意义

Clinical significance of serum albumin,blood urea nitrogen,creatinine blood lipid in patients with acute cerebrovascular disease

目的观察急性脑血管病患者血清白蛋白(Alb)、尿素氮(BUN)、肌酐(Cr)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)及低密度脂蛋白胆固醇(LDL-C)水平变化,并探讨其临床意义。方法检测61例急性脑血管病患者(患者组)及34例健康体检者(对照组)血清Alb、BUN、Cr、TG、TC、HDL-C、LDL-C。结果患者组血清Alb、TG、TC、HDL-C、LDL-C水平明显低于对照组(P<0.01);而BUN、Cr水平则极显著高于对照组(P<0.01)。结论急性脑血管病患者血清白蛋白及血脂明显降低,而BUN、Cr升高,其水平变化在临床上可作为病情评估、观察疗效、判断预后的指标。

Objective This study was undertaken to investigate the clinical significance of measurements of serum albumin, blood urea nitrogen, creatinine and blood lipid（including triglyceride, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol）in patients with acute cerebrovascular disease. Methods The study population consisted of 61 patients with aute cerebrovascular disease and 34 healthy control subjects. Serum albumin,blood ureanitrogen,creatinine,triglyceride, total cholesterol, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol were measured. Results Serum albumin,triglyceride,total cholesterol,high-density lipoprotein cholesterol and low-density lipoprotein cholesterol in patients with acute cerebrovascular disease were significantly lower that those in healthy controls（all P〈0. 01 ）. The blood urea nitrogen and creatinine in patients with acute cerebrovascular disease wrer significanty higher than those in healthy controls. Conclusion The measurements of serum albumin, blood urea nitrogen , creatinine and blood lipid can be used for the evaluation of treatment effect and prognosis in patients with acute cerebrovascular disease.