肝动脉内导管留置碘油完全充填法治疗巨大肝癌

Indwelling hepatic arterial catheter of fulfilling lipiodol treatment for giant primary hepatic carcinomas

目的探讨巨大肝癌介入治疗的策略与方法及肝动脉内留置导管分次碘油栓塞的价值。方法16例巨大肝癌患者,首次治疗采用肝动脉内留置导管分次碘油栓塞治疗,共行40次介入治疗,平均每例2.5次。观察患者介入术后肝功能损害及近期疗效。结果16例患者介入术后均未出现严重肝功能损害,经护肝治疗后均能平稳恢复。3个月后肿瘤缩小达PR9例,SD7例,无PD者。结论肝动脉内留置导管分次碘油栓塞治疗巨大肝癌不会造成严重肝损伤,并使肝癌尽快得到完全栓塞,有临床实用价值。

Objective To investigate the clinical value of indwelling hepatic arterial catheter in splitting fullfilling of lipiodol treatment for giant primary hepatic carcinomas, Methods Sixteen patients with giant primary hepatic carcinomas under DSA guidance, splitting lipiodol embolizations were carried out through indwelling hepatic arterial catheter everyday until the lipiodol with fulfilling the tumors, Total forty times （average 2.5 individually）of interventional treatment were accomplished in these patients, Liver function and short-term effect after interventional therapy were observed. Results None of these 16 patients had serious liver function damage and recovered uneventfully after general protective care. PR and SD were achieved in 9 and 7 cases respectively, 3 months after this interventional procedure, PD was not found. Conclusions Indwelling hepatic arterial catheter in fulfilling of lipiodol treatment for giant primary hepatic carcinomas is not only unlikely to cause serious liver function damage, but also can completely embolize the tumor quickly, therefore worthy to be recommended clinic ally.