摘要
目的:利用双水相体系分离纯化黄芩苷,探究萃取机理。方法:通过实验选择非离子表面活性剂聚乙二醇(PEG)-K2HPO4-H2O双水相体系的成相条件及温度,pH值,聚合物的分子量等不同因素对黄芩苷得率的影响。结果:黄芩苷在最佳分离条件下的萃取率为98.6%。结论:按本文方法所形成双水相体系,操作简便,萃取率高,方法重现性好,可适用工业化生产。
AIM ： To explore the extraction mechanism of the separation-purification of baicalin in aqueous twophase systems. METHODS： By experiment, nonionic surfactant PEG-K2PHO4-H2O two aqueous phase system was selected to phase-forming conditions, and the effect of temperature, pH, salt composition on partition of baicalin PEG/sah system. RESULTS： The extraction rate of baicalin in aqueous two-phase system was up to 98.6%. CONCLUSION： The two aqueous phase system for baicalin extraction is easy to operate has good reproductivity, and can be applied in mass production.
出处
《中成药》
CAS
CSCD
北大核心
2008年第4期498-501,共4页
Chinese Traditional Patent Medicine
关键词
黄芩苷
双水相萃取
聚乙二醇
baicalin
aqueous two-phase extraction
poly ethylene glycol （PEG）
