补肾壮骨方治疗绝经后骨质疏松症的临床研究

Clinical Study on Treatment of Postmenopausal Osteoporosis by Bushenzhuanggu Prescription

目的:观察补肾壮骨方治疗绝经后骨质疏松症的临床疗效。方法:60例病例随机分为两组,治疗组用补肾壮骨方,对照组用阿仑膦酸钠(福善美)治疗,3个月后比较疗效。结果:治疗组总有效率96.7%,明显高于对照组。在改善症状、提高骨密度、改善骨代谢、提高性激素水平方面,治疗组均优于对照组,差异有显著性(P<0.01)结论:补肾壮骨方能有效缓解绝经后骨质疏松症的临床症状,提高骨密度,改善骨代谢,同时提高性激素水平,是一个值得推广的方剂。

Objective： To observw the effect of Bushenzhuanggu prescription （BSZGP） in treating postmenopausal osteopo- rosis. Methods： Sixty cases of postmenopausal osteoporosis were randomly divided into the treated group （30 cases given BSZGP） and the control group （30 cases given sodium alendronate）. All patients were followed up for 3 months and the effects were compared. Results： The total effective rate was 96.7% in treated group which was obviously higher than that of the control group. There were significant differences between the two groups in clinical symptoms, bone mineral density （BMD）, the relative biochemical indications of bone metabolism and sex hormone level, which showed an obvious advantage in treated group over the control group. Conclusion： BSZGP could effectively ameliorate the clinical symptoms of postmenopausal osteoporosis, increase BMD, improve bone metabolism as well as enhance the sex hormone level, revealing that BSZGP deserves more widely application in the future.