生长抑素在不同种属动物胃肠道分布的实验研究

A STUDY ABOUT THE DISTRIBUTION OF SOMATOSTATIN IN GASTROINTESTINAL TRACT OF VARIOUS ANIMALS

目的旨在从生物进化角度探讨生长抑素在胃肠胰系统、包括阑尾、胆囊和脾脏在内的分布情况。方法应用放射免疫分析法系统探测生长抑素在小鼠、狗、猴和胎儿阑尾、胆囊和脾脏的分布。结果探测结果显示在不同哺乳类动物阑尾、胆囊和脾脏内有大量生长抑素分布。在小鼠、狗阑尾内生长抑素含量间有显著性差异（Ｐ＜０．０５），在狗和胎儿阑尾内生长抑素含量间无显著性差异。生长抑索在狗的阑尾和回肠、空肠、盲肠间无显著性差异。结论：小鼠、狗和胎儿阑尾有大量生长抑素分布。狗。

Aims and methods From the point of biological evolution,We strdy the distribrtion of somatostatin in gastrointestinal including appendix,spleen ,and gall bladder,The method of determination is radio-immuno-assay. Results:The results showed that higher amounts of SS contained in the appendix ,spleen and gall bladder of many kinds of animals .SS content in the appendix was obvious difference between mouse and dog (P<005),There was no obvious difference ,between dog and fetals .SS Content in appendix of dog was no obvious diffence ,Compared with in jejunum,ileum, caecum.[WT5”HZ〗Conclusions:It is suggested that SS concentration in appendix of many kinds of animals and fetals was higher.No report about SS Content of appendix can he found in foreign and china tefore.