功能性消化不良病人幽门螺杆菌感染率调查

THE INCIDENCE OF HELICOBACTER PYLORI INFECTION IN PATIENTS WITH FUNCTIONAL DYSPEPSIA

目的调查功能性消化不良病人幽门螺杆菌感染情况，以了解功能性消化不良的病因。方法对２２４４例功能性消化不良病人进行血清幽门螺杆菌抗体检测。结果（１）功能性消化不良病人幽门螺杆菌感染率为６８１％（１５２８／２２４４），其中男性７５６例，占３３９６％，女性７５９例，占３３８２％。（２）３０—３９年龄组幽门螺杆菌感染率最高，达７２１％，以后随年龄增长有逐渐下降趋势，７０年龄组阳性率为５０５％。结论①幽门螺杆菌感染可能与功能性消化不良的症状有关。②幽门螺杆菌感染不是持续存在的。③幽门螺杆菌感染率无性别差异。

Aims To investigate the incidence of Helicobacter pylori(HP) infection in patients with functional dyspepsia (FD) and the cause of FD. Methods: An ELISA technique was used to detect circulating HP IgG antibodies in 2244 patients with FD. Results: The overall incidence of HP infection in FD patients was 68.1% (1528/2244), nearly one third of FD patients were not associated with HP infection. The highest incidence of HP infection was in 30～39 group (72.1%) and then decreased slowly with the age. The positive rates of HP were 69.4% (756/1110) in male and 66.9% (759/1134) in female respectively. Conclusions: The results suggested that HP infection may be one of the reasons of FD. HP infection is not persistent in human body. There is no remarkably difference in HP infection between male and female.