中晚期肝癌癌灶完全消失的影响因素初探

Preliminary Study of Infleuncing Factors of Complete Intrahepatic Tumor Disappearance (CITD)in Middle-advanced Liver Cancer Patients

５２例中晚期肝癌，经放射治疗、介入治疗（１９例）、瘤内药物注射（４６例）、中药治疗后４０例肝癌灶完全消失。在一定放射剂量下（＞１１Ｇｙ），ＴＮＭ分期（肿瘤的累及范围）（Ｐ＜００１），肿块大小（Ｐ＜０００１），影响肝癌灶的完全消失率。肿块越大，累及范围越广，则消失率越低。介入治疗对肿块单个、直径＞９ｃｍ≤１３ｃｍ者，能提高癌灶的完全消失率。对治疗后直径≤３ｃｍ癌灶。

Four hundred and fifty-two patients with middle-advanced liver cancer were treated by radiotherapy,interventional therapy(19 cases),percutaneous drug injection (46 cases) and Chinese herbs,of which 40 were achieved complete intrahepaitc tumor disappearance (CITD).Under certain radiation dose(>11Gy),tumor infiltrating extent (TNM classification)(p<0.01),tumor diameter(p<0.001)effect CITD.The larger tumor diameter and infiltrating extent are the lower possibility they can be achieved CIDT.CIDT can be enhanced by intrahepatic interventional therapy for those with single tumor size more than 9 cm and by intrahepatic tumor injection for those with tumor size not more than 3 cm after other treatments.