抑郁症对冠心病患者预后的影响

Correlation between Depression and Prognosis in Patients with Coronary Heart Disease

目的分析抑郁症对冠心病患者预后的影响。方法将246例冠心病患者分为抑郁症组和非抑郁症组,比较两组患者近期心血管事件发生率,分析抑郁症与心血管事件的关系。结果冠心病合并抑郁症患者心绞痛、急性ST段抬高型心梗、急性非ST段抬高型心梗、心力衰竭、短阵室性心动过速、心室颤动、心脏性死亡的发生率分别为75.6%、11.1%、17.8%、26.7%、12.2%、8.9%和7.8%,抑郁症为心血管事件发生的独立预测因素。结论冠心病合并抑郁症患者心血管事件发生率升高,且抑郁症为心血管事件发生的独立预测因素。

Objective To investigate primarily the correlation between depression and prognosis in patients with coronary heart disease （CHD）. Methods 246 CHD patients were dJvided Jnto the depression group and non-depression group. The relation between depression and incidence of short term cardiovascular events was compared. Results The incidence of angina pectoris, ST-segment elevated myocardial infarction, non ST-segment elevated myocardial infarction, congestive heart failure, ventricular tarchycardia, ventricular fibrillation and sudden death in the near future were 75.6%, 11.1%, 17.8%, 26.7%, 12.2%, 8.9% and 7.8% respectively. Depression was an independent predictive factor of all cardiovascular events. Conclusion CHD patients complicated by depression have a high incidence of cardiovascular events, and the depression is an independent predictive factor of all cardiovascular events.