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rasp21、bFGF在子宫肌瘤患者子宫内膜组织中的表达及意义 被引量:2

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摘要 选取60例子宫肌瘤患者(肌瘤组)和20例健康查体妇女(对照组),采用免疫组化法测定其子宫内膜组织中ras癌基因p21蛋白(rasp21)和碱性成纤维细胞生长因子(bFGF)表达水平。结果rasp21、bFGF在肌瘤组黏膜下、肌壁间肌瘤子宫内膜中的表达高于对照组(P均〈0.05);rasp21在40-50岁及肿瘤直径〈5cm者子宫内膜中表达明显增高,rasp21、bFGF在增生期及有出血症状者中的表达分别高于分泌期和无出血症状者(P均〈0.05)。认为rasp21、bFGF是子宫肌瘤的促发因子,且与子宫肌瘤类型及雌激素水平有关。
作者 孙兰颖
出处 《山东医药》 CAS 北大核心 2008年第11期51-52,共2页 Shandong Medical Journal
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参考文献5

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