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肿瘤干细胞研究现状 被引量：5

Cancer stem cells:current status
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摘要 近年来,对肿瘤干细胞的研究已经成为热点。研究发现一小部分肿瘤细胞具有干细胞特性,即具有自我更新、无限增殖与分化潜能,这部分细胞就是肿瘤干细胞。目前已经在多种肿瘤中发现并鉴定出肿瘤干细胞,包括白血病、乳腺癌、脑肿瘤、肝癌、结肠癌等。本文就肿瘤干细胞的概念、存在证据、研究方法以及临床应用前景作一综述。 Recently,study on cencer stem cells has been a focus of study. Cancer stem cell is a small population of cencer cells possessing the properties of stem cells：self-renewal, differentiation and proliferation. To date, the existence of cancer stem cells has been proven in acute and chronic myeloid leukemia, breast cancer, brain tumors, liver cancer and colon cancer, etc.. In this article we reviews the current progress on cancer stem cells,including the defination, existing evidence, research methods, and challenges in clinical application.
作者 孙志刚 黄盛东 张宝仁
机构地区 第二军医大学长海医院胸心外科
出处 《第二军医大学学报》 CAS CSCD 北大核心 2008年第4期439-442,共4页 Academic Journal of Second Military Medical University
基金 国家自然科学基金(30471718) 上海市科学技术委员会科研计划资助项目(04JC14006)~~
关键词 肿瘤干细胞 细胞分离 细胞培养 细胞鉴定 cancer stem cells cell separation cell culture cell identification
分类号 R730.5 [医药卫生—肿瘤]
  • 相关文献

参考文献42

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二级参考文献15

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共引文献18

同被引文献70

  • 1钱莘,陈正堂.肺干细胞研究进展[J].中国肺癌杂志,2007,10(4):337-340. 被引量：3
  • 2于清蕊.干细胞与肿瘤干细胞[J].中国组织工程研究与临床康复,2007,11(15):2948-2951. 被引量：8
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引证文献5

二级引证文献2

第二军医大学学报
2008年 第4期

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