同种原位背驮式肝移植治疗Wilson病

Treatment of Wilson disease by piggy-back orthotopic liver transplantation

我院于1995年9月成功的施行一例同种原位背驮式（Piggy－back）肝移植。在动物实验的基础上，我们进一步改进了手术方法，在不离断第一、二肝门的情况下，完成第三肝门的分离。与传统的肝移植相比，本手术不离断肝后下腔静脉，不需静脉转流。术中血压稳定，血流动力学影响少，内环境干扰少为手术成功关键。该手术填补了我国肝移植外科技术的空白，为治疗良性晚期肝脏疾病又开辟了一新的途径。

Piggy-back orthotopic liver transplantation (PBOLT) was successfully performed in a patient with Wilson disease in Sep. 1995. On the basis of the animal experiment, the operative strategy was further improved. ixssection of the third hepatic portis was conducted without resecting the first and second hepatic portis. As compared with the standard procedures of orthotopic liver transplantation, PBOLT did not resect the inferior vena cava and did not need venovenous bypass. The key fcctors for the success of the operation included the stability of arterial pressure, little influence on the haemodynamic parameters and little disturbance of internal environment.