慢性前列腺炎前列腺液细菌检出和耐药性分析

Detection of pathogenic bacteria in prostatic secretion and analysis of their drug resistance

目的分析慢性前列腺炎致病菌的分布和耐药性。方法对282例慢性前列腺炎患者采用Meares-Stamey四段取样法进行作前列腺液细菌培养和药敏试验。结果282例前列腺液标本中共分离出致病菌59株,阳性率20.9%,其中以革兰阳性菌中凝固酶阴性葡萄球菌为主,共41株(69.5%);该菌对许多临床常用抗生素都呈不同程度耐药。结论对细菌性前列腺炎的治疗关键是在正确的病原学诊断和药物敏感试验指导下合理使用抗菌素。

Objective To study the pathogenic bacteria distribution and drug resistance of chronic prostatitis. Methods 282 cases of sufferers of chronic prostatitis received bacteria cultivation of prostatic secretion and susceptibility test by Meares- Stamey method. Results Of the 282 samples of prostatic secretion, 59 strains of pathogenic bacteria were separated and positive rate was 20.9%, which were mainly coagulase-negative Staphylococcus （41 strains, positive rate was 69.5%）. These pathogenic bacteria were more or less drug resistant to common antibiotics. Conclusion The key to the treatment of chronic bacterial prostatitis is the proper employment of antibiotics under the correct guidance of aetiological diagnosis and drug-sensitive experiment.