摘要
目的探讨中药在基因水平调整过敏体质的机制。方法选择花粉症、哮喘、特应性皮炎患者为研究对象,应用扶正固本中药进行治疗,疗程为6个月;观察治疗前后IgE高亲和力受体β链基因(FcεRIβ)、白介素5受体α链基因(IL-5Rα)、人类白细胞抗原(HLA-A)表达以及临床症状、免疫球蛋白E(IgE)等的变化情况。结果各治疗组治疗前后基因表达均有改变,临床症状、IgE亦有改善。结论提示中药可以改变体内高致敏状态,缓解青少年过敏症状。
Objective To evaluate the adjusting effects of herbs on atopy. Methods The trial involved patients with hay fever, atopic dermatitis and asthma, who were treated by health-supporting therapy for six months; the clinical symptoms,IgE and FcεRIβ, ILT-5Rα and HLA-A in blood were observed. Results The clinical symptoms, IgE and above genes were significantly improved after treatment. Conclusion The herbs are effective in adjusting atopy.
出处
《上海中医药杂志》
北大核心
2008年第4期49-51,共3页
Shanghai Journal of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(30100234)
