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血清甲壳质酶蛋白40诊治妇科恶性肿瘤研究 被引量:4

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摘要 寻找特异性的恶性肿瘤血清标志物对于恶性肿瘤的早期诊断、病情监测、判断预后和治疗后随访等具有重要意义。研究发现,甲壳质酶蛋白40(YKL-40)与多种恶性肿瘤细胞的增值、分化、凋亡以及血管形成和组织重塑关系密切。YKL-40在多种恶性肿瘤中有特异性表达,其血清水平与肿瘤的诊断、治疗监测、患者预后判断和靶向治疗具有极强的相关性。多种妇科肿瘤患者血清中可以检测到该蛋白的表达。就其与妇科恶性肿瘤的关系作综述。
作者 范江涛 李力
出处 《国际妇产科学杂志》 CAS 2008年第2期101-104,共4页 Journal of International Obstetrics and Gynecology
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同被引文献46

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